A clomiphene challenge test is a dynamic type of test that can discover some cases of poor ovarian reserve that are still showing a normal day 3 FSH.
This test is done by:
1. Obtaining a day 3 FSH and estradiol
2. The woman takes two tablets of clomiphene (100 mg) on days 5-9 of the cycle
3. Repeat an FSH level on day 10 of the cycle
The normal test would show a low FSH on day 3, a low estradiol on day 3 and also a low FSH on day 10.
Cut off values for the day 3 and the day 10 FSH values are very lab dependent and must be determined by experience with the laboratory being used. In other words, only your infertility specialist can interpret your results.